But Madrid were in front three minutes later as Casemiro chopped a cross into the ground, and as it bounced up Ronaldo rose highest to head into the net.
Cristiano Ronaldo recorded his 42nd career hat-trick in style as Real Madrid took a commanding first-leg lead over Atletico Madrid. Lucas Vazquez did well to get in round the back and find Ronaldo, who had time to take a touch and send Oblak the wrong way.
The Champions League season continued with the first legs of the semi-finals, played in midweek.
Ronaldo's frustrations are understandable given what he's done at the Santiago Bernabeu, but it's part and parcel of playing for Real Madrid. However, there's still the second leg and we'll have to work hard and battle and we're sure to have to dig in there.
Speaking to reporters at the post-match press conference, Zidane enthused "I don't know whether it's all down to him being rested. I'm happy and I want to give my best in the years I have left on my contract, score more goals and help Real Madrid to win titles".
"It was a total game from the team, we played phenomenally well", he told the press, according to ESPN FC.
"Atletico" another trend is the Diego Simeone's side won the first match (the "Bayer" and "Lester"), and then quietly in a favorite dry-style game.
Ronaldo has now scored more goals in Champions League knockout games (52) than in group stage fixtures (51), while he now has 103 Champions League goals, which is more than Atleti's total as a club (100).
The loss was a continuation of results Atletico have suffered in continental competitions against Real since the European Cup semi-final in 1959, despite coach Diego Simeone's reign bringing more balance to the rivalry.
"It seems impossible, but it is football and football has these unexpected things that make it marvellous". We deserved a complete game against them.
"The domination the team showed yesterday on the pitch shows how fresh our players are, we are very motivated and we want to go to the Champions League final".
Madrid is trying to beat Atletico in the Champions League for the fourth straight time.