More than 125 firefighters were on the scene and that water-dropping helicopters were being used, the newspaper said.
The fire broke out before dawn Wednesday on the east side of Interstate 405 in the Sepulveda Pass and raced up steep slopes into neighbourhoods at the top.
"These are days that break your heart but also days that shows the resilience of our city", he said.
Winds are now blowing toward the south, southwest, which has put the Westridge-Canyonback Wilderness Park and the Brentwood neighborhood north of Sunset Boulevard on notice.
"This fire is very unsafe and spreading rapidly, but we'll continue to attack it with all we've got", Brown said, according to the Los Angeles Times. "We have mobilized additional resources to the impacted areas, and we are working to restore electric service as quickly and safely as possible", said SCE CEO Kevin Payne.
Strong winds were hindering the deployment of firefighting aircraft, according to fire officials.
Farther north, in Santa Clarita, firefighters were making significant gains against the Rye fire that had burned toward Magic Mountain on Tuesday afternoon.
The Creek Fire was the second blaze to erupt.
Nicknamed the Skirball Fire, it was reported at 5 a.m. near Mulholland Drive, a five-minute drive from the Skirball Cultural Center.
The biggest and most destructive of several wildfires burning in Southern California has scorched more than 101 square miles.
US President Donald Trump tweeted a message of "thoughts and prayers" to California as it nears the end of its deadliest year ever for wildfires.
State fire authorities say the fire burning in Ventura County about 60 miles northwest of Los Angeles is also considered a threat to 12,000 structures Wednesday. "With winds like this, it can be anything", Garcetti said, referring to the powerful Santa Ana winds that continued to blow across the region.
Evacuations have been ordered and a wider area has been told to be ready for orders to leave.
At around 6 a.m., sheriff's deputies and Los Angeles Police Department officers began evacuations in the 12300 block of Little Tujunga Road down to Foothill Boulevard, according to the LAPD.
The fire has destroyed at least 30 homes and scorched 11,377 acres, authorities said.