West Brom are rated at 11/4 for the victory at Goodison Park.
The Toffees are still looking for their first win of 2018, having lost their previous four matches and failed to win any of their last six.
It was a solid team performance from West Brom with every player contributing to the win.
Long-term absentee Ramiro Funes-Mori will continue to sit things out, whilst the Toffees are nearly back to full strength after an injury crisis in the early part of the season.
It was "surreal", according to Walcott - but also symbolic of how his Arsenal career fizzled out, with not a single league start this season as he became a peripheral figure at a club he joined when he was just 16.
The 30-year-old has only started nine Premier League games this season for the Toffees, with the last of those coming in the 2-1 defeat to Bournemouth on December 30. "It's our home games that will determine our future, but on the away games we've got to win the odd game and pick up as many points as possible".
This is the first time these sides will meet at Goodison Park in a top-flight match with both sides managed by Englishmen since September 1981, when Everton were managed by Howard Kendall and West Brom managed by Ronnie Allen. He gave me the opportunity to springboard and score that many goals for the club, and no-one can take that away from me.
Southampton are winless in 10 league games are a point and a place above the relegation zone while Tottenham are fifth.
The 28-year-old forward spent 12 years at Arsenal, and posted a montage of images from his days playing for the Gunners on Twitter, before later recording a video message for Instagram in which he thanked fans for their support.